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VisionArray MYCO Chip

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VisionArray® MYCO Chip – Fast and Reliable Genotyping


The genus Mycobacterium comprises more than 140 species, which, for the purpose of diagnosis and treatment, has been grouped into three categories: M. tuberculosis complex (MTC), M. leprae, and nontuberculous mycobacteria (NTM). In the WHO European region, approximately 300,000 tuberculosis cases have been notified in 2016. The majority of the Mycobacterium species belongs to the NTM group and many of these bacteria cause life-threatening infections in humans. Pulmonary manifestations account for 80-90% of all NTM-associated diseases and the differentiation between tuberculosis pathogens and NTM is essential for diagnosis and treatment. No standard treatment of NTMs exists. Therefore, a clear distinction between the present species is of highest importance.



VisionArray ® MYCO Chips


VisionArray ® MYCO Chip 1.0


VisionArray MYCO Chip

The VisionArray MYCO Chip 1.0 is intended to be used with a VisionArray Analysis Package for the qualitative detection and identification of PCR amplicons of the genera Mycobacterium, Mycobacteriodes, Mycolicibacillus, Mycolicibacter, and Mycolicibacteriumas well as several additional clinically relevant mycobacterial species that have been produced with the help of the VisionArray MYCO Primer Kit 1.0 or the VisionArray MYCO PreCise Master Mix.


 

Ordering Information


Prod. No.

TestsIntended Use1

VA-0003-10

10CE IVD

VA-0003-50

50CE IVD

1CE IVD only available in certain countries. All other countries research use only! 

Please contact your local dealer for more information.

 

Download Information



DATASHEET


MANUAL


MYCO CHIP FILE

 

 


VisionArray ® MYCO PreCise Master Mix


PreCise Master Mix

The VisionArray MYCO PreCise Master Mix is a ready to use PCR Master Mix for amplifying ITS and, in case of M. tuberculosis complex, IS6110 region of mycobacterial genomes including but not limited to those detected by the VisionArray MYCO Chip. The VisionArray MYCO PreCise Master Mix contains the VisionArray MYCO Primer Mix 1.0, dNTP/dUTP Solution, the VisionArray PreCise Taq DNA Polymerase, the PCR-Buffer, MgCl2, and the VisionArray Uracil-DNA Glycosylase. During PCR, specific sections of the ITS and IS6110 region of the mycobacterial genomes will be biotinylated. The hybridization and detection of the amplified sequences is subsequently performed using the VisionArray Detection Kit and the VisionArray MYCO Chip.


 

Ordering Information


Prod. No.

TestsIntended Use1

ES-0008-50

50CE IVD

1CE IVD only available in certain countries. All other countries research use only! 

Please contact your local dealer for more information.

 

Download Information



DATASHEET


MANUAL


MSDS


SHORT PROTOCOL

 

 


VisionArray ® MYCO Primer Kit 1.0


MYCO Primer Kit 1.0

The VisionArray MYCO Primer Kit 1.0 is intended to be used for amplifying ITS and, in case of M. tuberculosis complex, IS6110 region of mycobacterial genomes including but not limited to those detected by the VisionArray MYCO Chip. During PCR, specific sections of the ITS and IS6110 region of the mycobacterial genomes will be biotinylated. The hybridization and detection of the amplified sequences are subsequently performed using the VisionArray Detection Kit and the VisionArray MYCO Chip. The VisionArray MYCO Primer Kit 1.0 includes the VisionArray MYCO Primer Mix 1.0 with high sensitivity for all mycobacteria species.


 

Ordering Information


Prod. No.

TestsIntended Use1

VP-0002-50

50CE IVD

1CE IVD only available in certain countries. All other countries research use only! 

Please contact your local dealer for more information.

 

Download Information



DATASHEET


MANUAL


MSDS


SHORT PROTOCOL

 

 


VisionArray ® PreCise Taq DNA Polymerase


PreCise Taq DNA Polymerase

The VisionArray PreCise Taq DNA Polymerase is a high quality heat stable Taq polymerase intended to be used for the specific amplification of a wide range of DNA fragments. The enzyme has hot-start capabilities, reduces false positives, amplifies low-level target sequences, and promotes amplification of a variety of templates. Further on, necessary for successful Mycobacterium genotyping is the use of the VisionArray MYCO Primer Kit 1.0 in combination with the VisionArray Uracil-DNA Glycosylase. Hybridization and detection of the amplified sequences is performed subsequently using the VisionArray Detection Kit and the VisionArray MYCO Chip 1.0.


 

Ordering Information


Prod. No.

TestsIntended Use

VE-0001-100

100CE IVD

 

Download Information



DATASHEET


MANUAL


MSDS


SHORT PROTOCOL

 

 


VisionArray ® Uracil-DNA Glycosylase


Uracil-DNA Glycosylase

The VisionArray Uracil-DNA Glycosylase is an E. coli derived glycosylase intended to be used to prevent carry-over contaminations from previous reactions. This is based on the principle of substituting dUTPs for dTTPs during PCR. Therefore, the PCR amplicon can be "discriminated" from the initial DNA strand. Incubating the PCR mixture with the UDG enzyme at elevated temperatures under alkaline conditions (during the initial denaturation step) will remove contaminating U-DNA from the sample, thereby, avoiding false positive results.


 

Ordering Information


Prod. No.

TestsIntended Use

VE-0002-100

100CE IVD

 

Download Information



DATASHEET


MANUAL


MSDS


SHORT PROTOCOL

 

 


VisionArray ® Detection Kit


VisionArray Detection Kit

The VisionArray Detection Kit is designed for the qualitative detection of specific DNA sequences produced with the VisionArray MYCO Primer Kit 1.0, the VisionArray PreCise Taq DNA Polymerase, the VisionArray Uracil-DNA Glycosylase, and the corresponding VisionArray MYCO Chip. The VisionArray Detection Kit contains all reagents that are required for the simple and fast hybridization and detection of PCR products on the VisionArray MYCO Chip.


 

Ordering Information


Prod. No.

TestsIntended Use1

VK-0003-50

50CE IVD

 


Prod. No.

Product

E-4051-1

Mini Slide Centrifuge 

1CE IVD only available in certain countries. All other countries research use only! 

Please contact your local dealer for more information.

 

Download Information



DATASHEET


MANUAL


MSDS


SHORT PROTOCOL

 

 


VisionArray ® Analysis Packages


VisionArray ® Analysis Package MultiScan


VisionArray Analysis Package MultiScan

The VisionArray Analysis Package MultiScan stands for a simple visualization and quick analysis of up to six VisionArray Chips in a single run. The VisionArray Analyzer Software MultiScan can thereby analyze HPV and MYCO specific Chips simultaneously. Only a few minutes will pass from scan to report.


 

Ordering Information


Prod. No.

Intended Use1

E-4070-1

CE IVD

1CE IVD only available in certain countries. All other countries research use only! 

Please contact your local dealer for more information.

 

Download Information



DATASHEET


MANUAL


SHORT PROTOCOL

 

 

VisionArray ® Analysis Package SingleScan


VisionArray Analysis Package SingleScan

The VisionArray Analysis Package SingleScan stands for a simple visualization and a quick analysis of the VisionArray Chip data. The analysis of a chip and the report of the results can be achieved in just a few minutes.


 

Ordering Information


Prod. No.

Intended Use1

E-4060-1

CE IVD

1CE IVD only available in certain countries. All other countries research use only! 

Please contact your local dealer for more information.

 





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