Plastem Supplement for Cell Culture (SCC)

PLASTEM® GRIFOLS EXPERTISE IN HUMAN PLASMA AT YOUR SERVICE

CONSISTENCY

PLASTEM® has no batch-to-batch variation. Manufactured from plasma pools containing more than 1000 donations.

PERFORMANCE

PLASTEM® is derived from human plasma which can be used for cell culture supplementation and supports the growth of several cell lines.

Cell lines grown with PLASTEM® include:

Human mesenchymal stem cells (hMSCs)2

Peripheral blood mononuclear cells (PBMCs)

Induced pluripotent stem cells (iPSCs)

Bone marrow mononuclear cells (BM-MNCs)

Primary cell cultures

African green monkey kidney (Vero)

Human fetal lung (MRC-5)

BALB/c mouse myeloma (P3X63Ag8.653)

Chinese hamster ovary (CHO) cells

T Cells

QUALITY

Grifols Quality System, EMA and FDA license for production and commercialization of plasma derivatives.

O GMP production.

O Quality and safety of a human plasmaderived medicine applied to PLASTEM®.

O Grifols’ plasma derivatives are used in more than 90 countries.

SAFETY

O Plasma is collected from healthy donors in US-based FDA-licensed plasma centers and European based plasma centers.

O Manufactured using the same safety standards as plasma-derived IV therapeutic products, e.g. Albumin and Immunoglobulins.

O Specific production steps with viral inactivation capacity.

O Gamma irradiation treatment.